Circadian Variations of Infarct Size in STEM1

Circadian variations of infarct size in STEM1.

Circadian variations of infarct size in acute myocardial infarction.

BACKGROUND The circadian clock influences a number of cardiovascular (patho)physiological processes including the incidence of acute myocardial infarction. A circadian variation in infarct size has recently been shown in rodents, but there is no clinical evidence of this finding. OBJECTIVE To determine the impact of time-of-day onset of ST segment elevation myocardial infarction (STEMI) on in...

Circadian Dependence of Infarct Size and Acute Heart Failure in ST Elevation Myocardial Infarction

OBJECTIVES There are conflicting data on the relationship between the time of symptom onset during the 24-hour cycle (circadian dependence) and infarct size in ST-elevation myocardial infarction (STEMI). Moreover, the impact of this circadian pattern of infarct size on clinical outcomes is unknown. We sought to study the circadian dependence of infarct size and its impact on clinical outcomes i...

Modification of infarct size.

To the Editor: The article by Maroko and his co-workers entitled "Factors Influencing Infarct Size Following Experimental Coronary Artery Occlusions" (Circulation 43:67, 1971) is indeed a very interesting one and an enthusiastic approach to the problem of modification of the size of an infarct. However, there are several points with regard to the methods that seem to need some clarification. Th...

Circadian variation in acute myocardial infarct size assessed by cardiovascular magnetic resonance in reperfused STEMI patients

OBJECTIVE Clinical studies using serum cardiac biomarkers to investigate a circadian variation in acute myocardial infarct (MI) size in ST-segment elevation myocardial infarction (STEMI) patients reperfused by primary percutaneous coronary intervention (PPCI) have produced mixed results. We aimed to investigate this phenomenon using acute MI size measured by cardiovascular magnetic resonance (C...